Structure of PDB 3c5j Chain B Binding Site BS01
Receptor Information
>3c5j Chain B (length=182) Species:
9606
(Homo sapiens) [
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RPRFLELLKSECHFFNGTERVRFLERYFHNQEEFVRFDSDVGEYRAVTEL
GRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTVQRRVHPQVTVYP
AKHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTL
VMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
Ligand information
>3c5j Chain C (length=13) Species:
9606
(Homo sapiens) [
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QVIILNHPGQISA
Receptor-Ligand Complex Structure
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PDB
3c5j
The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
L11 S13 F26 E28 Y30 W61 K71 Y78 H81 N82 V85
Binding residue
(residue number reindexed from 1)
L8 S10 F23 E25 Y27 W58 K68 Y75 H78 N79 V82
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0002250
adaptive immune response
GO:0002504
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0005764
lysosome
GO:0005765
lysosomal membrane
GO:0005768
endosome
GO:0010008
endosome membrane
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:3c5j
,
PDBe:3c5j
,
PDBj:3c5j
PDBsum
3c5j
PubMed
18697946
UniProt
B8YAC7
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