Structure of PDB 3c5j Chain B Binding Site BS01

Receptor Information
>3c5j Chain B (length=182) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPRFLELLKSECHFFNGTERVRFLERYFHNQEEFVRFDSDVGEYRAVTEL
GRPVAESWNSQKDLLEQKRGQVDNYCRHNYGVVESFTVQRRVHPQVTVYP
AKHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNGDWTFQTL
VMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3c5j The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
L11 S13 F26 E28 Y30 W61 K71 Y78 H81 N82 V85
Binding residue
(residue number reindexed from 1)
L8 S10 F23 E25 Y27 W58 K68 Y75 H78 N79 V82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0002250 adaptive immune response
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:3c5j, PDBe:3c5j, PDBj:3c5j
PDBsum3c5j
PubMed18697946
UniProtB8YAC7

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