Structure of PDB 3c3l Chain B Binding Site BS01

Receptor Information

>3c3l Chain B (length=1085) Species: 2886925 (Escherichia phage N4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GIDAVYPSLVGTADSKAEGIKNYFKLSFTLPEEQKSRTVGSEAPLKDVAQ
ALSSRARYELFTEKETANPAFNGEVIKRYKELMEHGEGIADILRSRLAKF
LNTKDVGKRFAQGTEANRWVGGKLLNIVEQDGDTFKYNEQLLQTAVLAGL
QWRLTATSNTAIKDAKDVAAITGIDQALLPEGLVEQFDTGMTLTEAVSSL
AQKIESYWGLSRNPNAPLGYTKGIPTAMAAEILAAFVESTDVVENIVDMS
EIDPDNKKTIGLYTITELDSFDPINSFPTAIEEAVLVNPTEKMFFGDDIP
PVANTQLRNPAVRNTPEQKAALKAEQATEFYVHTPMVQFYETLGKDRILE
LMGAGTLNKELLNDNHAKSLEGKNRSVEDSYNQLFSVIEQVRAQSEDIST
VPIHYAYNMTRVGRMQMLGKYNPQSAKLVREAILPTKATLDLSNQNNEDF
SAFQLGLAQALDIKVHTMTREVMSDELTKLLEGNLKPAIDMMVEFNTTGS
LPENAVDVLNTALGDRKSFVALMALMEYSRYLVAEDKSAFVTPLYVEADG
VTNGPINAMMLMTGGLFTPDWIRNIAKGGLFIGSPNKTMNEHRSTADNND
LYQASTNALMESLGKLRSNYASNMPIQSQIDSLLSLMDLFLPDINLGENG
ALELKRGIAKNPLTITIYGSGARGIAGKLVSSVTDAIYERMSDVLKARAK
DPNISAAMAMFGKQAASEAHAEELLARFLKDMETLTSTVPVKRKGVLELQ
STGTGAKGKINPKTYTIKGEQLKALQENMLHFFVEPLRNGITQTVGESLV
YSTEQLQKATQIQSVVLEDMFKQRVQEKLAEKAKDPTWKKGDFLTQKELN
DIQASLNNLAPMIETGSQTFYIAGSENAEVANQVLATNLDDRMRVPMSIY
APAQAGVAGIPFMTIGTGDGMMMQTLSTMKGAPKNTLKIFDGMNIGLNDI
TDASRKANEAVYTSWQGNPIKNVYESYAKFMKNVDFSKLSPEALEAIGKS
ALEYDQRENATVDDIANAASLIERNLRNIALGVDIRHKVLDKVNLSIDQM
AAVGAPYQNNGKIDLSNMTPEQQADELNKLFREEL

Ligand information

>3c3l Chain D (length=19) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tcaaaagaagcggagcttc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3c3l Structural basis for DNA-hairpin promoter recognition by the bacteriophage N4 virion RNA polymerase.
Resolution	2.4 Å
Binding residue (original residue number in PDB)	K114 R119 W129 K176 I181 T202 T204 E205 K267 T269 G271 R318 R421 I675 Y678 S680 K688 K849 K850 E886 D901 R902 R904 P921 I925
Binding residue (residue number reindexed from 1)	K104 R109 W119 K166 I171 T192 T194 E195 K257 T259 G261 R308 R411 I665 Y668 S670 K678 K839 K840 E876 D891 R892 R894 P911 I915

Enzymatic activity

Enzyme Commision number

2.7.7.6: DNA-directed RNA polymerase.

External links

PDB	RCSB:3c3l, PDBe:3c3l, PDBj:3c3l
PDBsum	3c3l
PubMed	19061645
UniProt	Q859P9\|RPOLV_BPN4 Virion DNA-directed RNA polymerase (Gene Name=50)

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