Structure of PDB 3bol Chain B Binding Site BS01

Receptor Information
>3bol Chain B (length=549) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRNRREVSKLLSERVLLLDGAYGTEFMKYGYDDLPEELNIKAPDVVLKVH
RSYIESGSDVILTNTFGATRMKLRKHGLEDKLDPIVRNAVRIARRAAGEK
LVFGDIGPTGELPYPLGSTLFEEFYENFRETVEIMVEEGVDGIIFETFSD
ILELKAAVLAAREVSRDVFLIAHMTFDEKGRSLTGTDPANFAITFDELDI
DALGINCSLGPEEILPIFQELSQYTDKFLVVEPNAGYPLKPHDFAVHIDS
YYELGVNIFGGCCGTTPEHVKLFRKVLGNRKPLQRKKKRIFAVSSPSKLV
TFDHFVVIGERINPAGRKKLWAEMQKGNEEIVIKEAKTQVEKGAEVLDVN
FGIESQIDVRYVEKIVQTLPYVSNVPLSLDIQNVDLTERALRAYPGRSLF
NSAKVDEEELEMKINLLKKYGGTLIVLLMGKDVPKSFEERKEYFEKALKI
LERHDFSDRVIFDPGVLPLGAEGKPVEVLKTIEFISSKGFNTTVGLSNLS
FLPDRSYYNTAFLVLGISKGLSSAIMNPLDETLMKTLNATLVILEKKEL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3bol Chain B Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3bol Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		C207 C272 C273
Binding residue
(residue number reindexed from 1)		C207 C262 C263
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.13: methionine synthase.
Gene Ontology
Biological Process
GO:0042558 pteridine-containing compound metabolic process
GO:0044237 cellular metabolic process

View graph for
Biological Process
External links
PDB RCSB:3bol, PDBe:3bol, PDBj:3bol
PDBsum3bol
PubMed18296644
UniProtQ9WYA5

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