Structure of PDB 3b6x Chain B Binding Site BS01

Receptor Information
>3b6x Chain B (length=125) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMTMEQFLTSLDMIRSGCAPKFKLKTEDLDRLRVGDFNFPPSQDLMCYTK
CVALMAGTVNKKGEFNAPKALAQLPHLVPPEMMEMSRKSVEACRDTHKQF
KESCERVYQTAKCFSENADGQFMWP
Ligand information
Ligand ID1BO
InChIInChI=1S/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3
InChIKeyLRHPLDYGYMQRHN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCCCO
ACDLabs 10.04OCCCC
FormulaC4 H10 O
Name1-BUTANOL;
BUTAN-1-OL
ChEMBLCHEMBL14245
DrugBankDB02145
ZINCZINC000001530354
PDB chain3b6x Chain B Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3b6x The role of multiple hydrogen-bonding groups in specific alcohol binding sites in proteins: insights from structural studies of LUSH.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		A52 T57 F64 T109 A110 F113
Binding residue
(residue number reindexed from 1)		A53 T58 F65 T110 A111 F114
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005549 odorant binding
GO:0005550 pheromone binding
GO:0035274 diphenyl phthalate binding
GO:0035275 dibutyl phthalate binding
GO:0035276 ethanol binding
Biological Process
GO:0007608 sensory perception of smell
GO:0007619 courtship behavior
GO:0019236 response to pheromone
GO:0042048 olfactory behavior
GO:0045471 response to ethanol
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:3b6x, PDBe:3b6x, PDBj:3b6x
PDBsum3b6x
PubMed18234222
UniProtO02372|OB76A_DROME General odorant-binding protein lush (Gene Name=lush)

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