Structure of PDB 3ax0 Chain B Binding Site BS01

Receptor Information
>3ax0 Chain B (length=78) Species: 79261 (Streptomyces castaneoglobisporus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVV
SHFDPVPTPRAAARAAVDELQGAPLLPF
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain3ax0 Chain B Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3ax0 A molecular mechanism for copper transportation to tyrosinase that is assisted by a metallochaperone, caddie protein
Resolution1.4 Å
Binding residue
(original residue number in PDB)		E67 H68 H82
Binding residue
(residue number reindexed from 1)		E22 H23 H37
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
Biological Process
GO:0042438 melanin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3ax0, PDBe:3ax0, PDBj:3ax0
PDBsum3ax0
PubMed21730070
UniProtQ83WS1

[Back to BioLiP]