Structure of PDB 3ask Chain B Binding Site BS01

Receptor Information
>3ask Chain B (length=211) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLYKVNEYVDARDTNMGAWFEAQVVRVTRKEDVIYHVKYDDYPENGVVQM
NSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRET
RTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGSPMVDNPMRRKSG
PSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCPLSSV
PSEDEWYCPEC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ask Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Resolution2.904 Å
Binding residue
(original residue number in PDB)
F152 Y188 D190 Y191 E193 Q330 L331 M332 D337 D356
Binding residue
(residue number reindexed from 1)
F20 Y39 D41 Y42 E44 Q181 L182 M183 D188 D204
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3ask, PDBe:3ask, PDBj:3ask
PDBsum3ask
PubMed22837395
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

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