Structure of PDB 3a79 Chain B Binding Site BS01

Receptor Information
>3a79 Chain B (length=525) Species: 7764,10090 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ESMVDYSNRNLTHVPKDLPPRTKALSLSQNSISELRMPDISFLSELRVLR
LSHNRIRSLDFHVFLFNQDLEYLDVSHNRLQNISCCPMASLRHLDLSFND
FDVLPVCKEFGNLTKLTFLGLSAAKFRQLDLLPVAHLHLSCILLDLVSYH
IKGGETESLQIPNTTVLHLVFHPNSLFSVQVNMSVNALGHLQLSNIKLND
ENCQRLMTFLSELTRGPTLLNVTLQHIETTWKCSVKLFQFFWPRPVEYLN
IYNLTITERIDREEFTYSETALKSLMIEHVKNQVFLFSKEALYSVFAEMN
IKMLSISDTPFIHMVCPPSPSSFTFLNFTQNVFTDSVFQGCSTLKRLQTL
ILQRNGLKNFFKVALMTKNMSSLETLDVSLNSLNSHAYDRTCAWAESILV
LNLSSNMLTGSVFRCLPPKVKVLDLHNNRIMSIPKDVTHLQALQELNVAS
NQLKSVPDGVFDRLTSLQYIWLHDNPWDCTCPGIRYLSEWINKHSGVVRN
SAGSVAPDSAKCSGSGKPVRSIICP
Ligand information
Receptor-Ligand Complex Structure
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PDB3a79 Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer
Resolution2.9 Å
Binding residue
(original residue number in PDB)
F317 L318 F319
Binding residue
(residue number reindexed from 1)
F285 L286 F287
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
Biological Process
GO:0002224 toll-like receptor signaling pathway
GO:0006955 immune response
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3a79, PDBe:3a79, PDBj:3a79
PDBsum3a79
PubMed19931471
UniProtQ4G1L3;
Q9EPW9

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