Structure of PDB 3a4k Chain B Binding Site BS01

Receptor Information
>3a4k Chain B (length=297) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPE
AIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQGNAGDVIALSKEFN
YGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTTK
SQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKKT
SVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEYW
KKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3a4k Structures of restriction endonuclease HindIII in complex with its cognate DNA and divalent cations
Resolution2.17 Å
Binding residue
(original residue number in PDB)
A118 N120 P149 T150 T151 K152 S153 Q154
Binding residue
(residue number reindexed from 1)
A116 N118 P147 T148 T149 K150 S151 Q152
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3a4k, PDBe:3a4k, PDBj:3a4k
PDBsum3a4k
PubMed19966419
UniProtP43870|T2D3_HAEIN Type II restriction enzyme HindIII (Gene Name=hindIIIR)

[Back to BioLiP]