Structure of PDB 2zsc Chain B Binding Site BS01

Receptor Information
>2zsc Chain B (length=123) Species: 5321 (Pleurotus cornucopiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDVQSSLTGTWYNELNSKMELTANKDGTLTGKYLSKVGDVYVPYPLSGRY
NLQPPAGQGVALGWAVSWENSKIHSATTWSGQFFSESSPVILTQWLLSSS
TARGDVWESTLVGNDSFTKTAPT
Ligand information
Ligand IDBTN
InChIInChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
InChIKeyYBJHBAHKTGYVGT-ZKWXMUAHSA-N
SMILES
SoftwareSMILES
CACTVS 3.385OC(=O)CCCC[CH]1SC[CH]2NC(=O)N[CH]12
CACTVS 3.385OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
ACDLabs 12.01O=C1NC2C(SCC2N1)CCCCC(=O)O
OpenEye OEToolkits 1.7.6C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2
OpenEye OEToolkits 1.7.6C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)O)NC(=O)N2
FormulaC10 H16 N2 O3 S
NameBIOTIN
ChEMBLCHEMBL857
DrugBankDB00121
ZINCZINC000035024346
PDB chain2zsc Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2zsc Tamavidins--novel avidin-like biotin-binding proteins from the Tamogitake mushroom
Resolution1.3 Å
Binding residue
(original residue number in PDB)		S18 Y34 S36 V38 W69 S76 T78 W96 D116
Binding residue
(residue number reindexed from 1)		S17 Y33 S35 V37 W68 S75 T77 W95 D115
Annotation score4
Binding affinityPDBbind-CN: -logKd/Ki=7.06,Kd=87nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2zsc, PDBe:2zsc, PDBj:2zsc
PDBsum2zsc
PubMed19187241
UniProtB9A0T7

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