Structure of PDB 2zpr Chain B Binding Site BS01

Receptor Information

>2zpr Chain B (length=221) Species: 8018 (Oncorhynchus keta) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

IVGGYECKAYSQPHQVSLNSGYHFCGGSLVNENWVVSAAHCYKSRVAVRL
GEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYV
QPVALPSSCAPAGTMCTVSGWGNTMSSTADGDKLQCLNIPILSYSDCNNS
YPGMITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYGCAEPG
NPGVYAKVCIFNDWLTSTMAT

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

2zpr Chain B Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2zpr A structural comparison of three isoforms of anionic trypsin from chum salmon (Oncorhynchus keta).
Resolution	1.75 Å
Binding residue (original residue number in PDB)	E52 N54 V57 E59 E62
Binding residue (residue number reindexed from 1)	E52 N54 V57 E59 E62
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	H40 D84 Q173 G174 D175 S176 G177
Catalytic site (residue number reindexed from 1)	H40 D84 Q173 G174 D175 S176 G177
Enzyme Commision number	?

Gene Ontology

	Molecular Function
GO:0004252	serine-type endopeptidase activity
GO:0008236	serine-type peptidase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006508	proteolysis

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space

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Cellular Component

External links

PDB	RCSB:2zpr, PDBe:2zpr, PDBj:2zpr
PDBsum	2zpr
PubMed	19564692
UniProt	B3Y8K5

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