Structure of PDB 2zpp Chain B Binding Site BS01

Receptor Information

>2zpp Chain B (length=30) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

FVNQHLCGSHLVEALYLVCGERGFFYTPKA

Ligand information

>2zpp Chain A (length=21) Species: 9823 (Sus scrofa) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

GIVEQCCTSICSLYQLENYCN

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2zpp An abnormal pK(a) value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis
Resolution	2.5 Å
Binding residue (original residue number in PDB)	V2 N3 Q4 H5 L6 C7 L11 L15 C19 R22 G23 F24 F25 P28
Binding residue (residue number reindexed from 1)	V2 N3 Q4 H5 L6 C7 L11 L15 C19 R22 G23 F24 F25 P28

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:2zpp, PDBe:2zpp, PDBj:2zpp
PDBsum	2zpp
PubMed	18725203
UniProt	P01315\|INS_PIG Insulin (Gene Name=INS)

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