Structure of PDB 2ze8 Chain B Binding Site BS01

Receptor Information

>2ze8 Chain B (length=226) Species: 358 (Agrobacterium tumefaciens)

MLLHLIYGPTCSGKTDMAIQIAQETGWPVVALDRVQCCPQIATGSGRPLE
SELQSTRRIYLDSRPLTEGILDAESAHRRLIFEVDWRKSEEGLILEGGSI
SLLNCMAKSPFWRSGFQWHVKRLRLGDSDAFLTRAKQRVAEMFAIREDRP
SLLEELAELWNYPAARPILEDIDGYRCAIRFARKHDLAISQLPNIDAGRH
VELIEAIANEYLEHALSQERDFPQWP

Ligand information

• Ligand ID: POP
• InChI: InChI=1S/H4O7P2/c1-8(2,3)7-9(4,5)6/h(H2,1,2,3)(H2,4,5,6)/p-2
• InChIKey: XPPKVPWEQAFLFU-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: O[P@@](=O)([O-])O[P@@](=O)(O)[O-]
  CACTVS 3.341: O[P]([O-])(=O)O[P](O)([O-])=O
  ACDLabs 10.04: [O-]P(=O)(O)OP([O-])(=O)O
  OpenEye OEToolkits 1.5.0: OP(=O)([O-])OP(=O)(O)[O-]
• Formula: H2 O7 P2
• Name: PYROPHOSPHATE 2-
• PDB chain: 2ze8 Chain B Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2ze8 Structural insight into the reaction mechanism and evolution of cytokinin biosynthesis.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): T10 C11 S12 G13 K14 T15
• Binding residue (residue number reindexed from 1): T10 C11 S12 G13 K14 T15
• Annotation score: 5

Enzymatic activity

• Enzyme Commision number: 2.5.1.27: adenylate dimethylallyltransferase (AMP-dependent).

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009824 AMP dimethylallyltransferase activity
• GO:0016740 transferase activity

Biological Process

• GO:0009691 cytokinin biosynthetic process

External links

• PDB: RCSB:2ze8, PDBe:2ze8, PDBj:2ze8
• PDBsum: 2ze8
• PubMed: 18258747
• UniProt: P58758|IPTZ_AGRFC Adenylate dimethylallyltransferase (Gene Name=tzs)