Structure of PDB 2z5g Chain B Binding Site BS01

Receptor Information
>2z5g Chain B (length=387) Species: 213419 (Geobacillus zalihae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLRANDAPIVLLHGLTGWGREEMFGFKYWGGVRGDIEQWLNDNGYRTYTL
AVGPLSSNWDRACEAYAQLVGGTVDYGAAHAAKHGHARFGRTYPGLLPEL
KRGGRIHIIAHSQGGQTARMLVSLLENGSQEEREYAKAHNVSLSPLFEGG
HHFVLSVTTIATPHDGTTLVNMVDFTDRFFDLQKAVLEAAAVASNVPYTS
QVYDFKLDQWGLRRQPGESFDHYFERLKRSPVWTSTDTARYDLSVSGAEK
LNQWVQASPNTYYLSFSTERTYRGALTGNHYPELGMNAFSAVVCAPFLGS
YRNPTLGIDDRWLENDGIVNTVSMNGPKRGSSDRIVPYDGTLKKGVWNDM
GTYNVDHLEIIGVDPNPSFDIRAFYLRLAEQLASLQP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2z5g Chain B Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2z5g Novel cation-pi interaction revealed by crystal structure of thermoalkalophilic lipase
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D61 H81 H87 D238
Binding residue
(residue number reindexed from 1)		D60 H80 H86 D237
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.3: triacylglycerol lipase.
Gene Ontology
Molecular Function
GO:0004806 triacylglycerol lipase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2z5g, PDBe:2z5g, PDBj:2z5g
PDBsum2z5g
PubMed17932933
UniProtQ842J9

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