Structure of PDB 2z4e Chain B Binding Site BS01

Receptor Information

>2z4e Chain B (length=303) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVV
SGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQ
DGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMG
PTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDG
ASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNR
CHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRP
FFP

Ligand information

>2z4e Chain I (length=5) Species: 9913 (Bos taurus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

GHRPY

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2z4e Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
Resolution	2.7 Å
Binding residue (original residue number in PDB)	L360 N364 M367 T368 W385 E397 R406 C407 H408 D432
Binding residue (residue number reindexed from 1)	L204 N208 M211 T212 W229 E241 R250 C251 H252 D276

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005102	signaling receptor binding

	Biological Process
GO:0007596	blood coagulation
GO:0030168	platelet activation
GO:0051258	protein polymerization

	Cellular Component
GO:0005577	fibrinogen complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:2z4e, PDBe:2z4e, PDBj:2z4e
PDBsum	2z4e
PubMed	17688324
UniProt	P02675\|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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