Structure of PDB 2z3m Chain B Binding Site BS01

Receptor Information
>2z3m Chain B (length=231) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFS
PGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEG
CASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGT
LFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACE
IPRRDYLNYLNQMRLGRLPNNFWVPRCLFSP
Ligand information
Ligand ID3D1
InChIInChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
InChIKeyOLXZPDWKRNYJJZ-RRKCRQDMSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3CC(C(O3)CO)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
ACDLabs 10.04n2c1c(ncnc1n(c2)C3OC(C(O)C3)CO)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3C[CH](O)[CH](CO)O3
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3C[C@@H]([C@H](O3)CO)O)N
FormulaC10 H13 N5 O3
Name(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol;
2'-DEOXYADENOSINE
ChEMBLCHEMBL449329
DrugBank
ZINCZINC000001081581
PDB chain2z3m Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2z3m Protein-based peptide-bond formation by aminoacyl-tRNA protein transferase
Resolution2.7 Å
Binding residue
(original residue number in PDB)		W49 Q188 H193
Binding residue
(residue number reindexed from 1)		W48 Q187 H192
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.2.6: lysine/arginine leucyltransferase.
Gene Ontology
Molecular Function
GO:0008914 leucyl-tRNA--protein transferase activity
GO:0016746 acyltransferase activity
GO:0016755 aminoacyltransferase activity
Biological Process
GO:0030163 protein catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2z3m, PDBe:2z3m, PDBj:2z3m
PDBsum2z3m
PubMed17891155
UniProtP0A8P1|LFTR_ECOLI Leucyl/phenylalanyl-tRNA--protein transferase (Gene Name=aat)

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