Structure of PDB 2yja Chain B Binding Site BS01

Receptor Information
>2yja Chain B (length=245) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2yja Design and Structure of Stapled Peptides Binding to Estrogen Receptors.
Resolution1.82 Å
Binding residue
(original residue number in PDB)
S305 I358 K362 L372 V376 E380 E542 M543
Binding residue
(residue number reindexed from 1)
S1 I54 K58 L68 V72 E76 E238 M239
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2yja, PDBe:2yja, PDBj:2yja
PDBsum2yja
PubMed21612236
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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