Structure of PDB 2yeq Chain B Binding Site BS01

Receptor Information
>2yeq Chain B (length=522) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APNFSSYPFTLGVASGDPLSDSVVLWTRLAPDPLNGGGMPKQAVPVKWEV
AKDEHFRKIVRKGTEMAKPSLAHSVHVEADGLEPNKVYYYRFKTGHELSP
VGKTKTLPAPGANVPQMTFAFASCQQYEHGYYTAYKHMAKEKLDLVFHLG
DYIYEYGPNEYVSKTGNVRTHNSAEIITLQDYRNRHAQYRSDANLKAAHA
AFPWVVTWDDHEVENNYANKIPEKGQSVEAFVLRRAAAYQAYYEHMPLRI
SSLPNGPDMQLYRHFTYGNLASFNVLDTRQYRDDQANNDGNKPPSDESRN
PNRTLLGKEQEQWLFNNLGSSTAHWNVLAQQIFFAKWNFGTSASPIYSMD
SWDGYPAQRERVINFIKSKNLNNVVVLTGDVHASWASNLHVDFEKTSSKI
FGAEFVGTSITSGGNGADKRADTDQILKENPHIQFFNDYRGYVRCTVTPH
QWKADYRVMPFVTEPGAAISTRASFVYQKDQTGLRKVSSTTIQGGVKQSD
EVEEDRFFSHNKAHEKQMIKKR
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain2yeq Chain B Residue 1524 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2yeq Crystal Structure of the Bacillus Subtilis Phosphodiesterase Phod Reveals an Iron and Calcium-Containing Active Site.
Resolution1.93 Å
Binding residue
(original residue number in PDB)		C124 D151 Y154 H382
Binding residue
(residue number reindexed from 1)		C124 D151 Y154 H382
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.1: alkaline phosphatase.
Gene Ontology
Molecular Function
GO:0004035 alkaline phosphatase activity
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:2yeq, PDBe:2yeq, PDBj:2yeq
PDBsum2yeq
PubMed25217636
UniProtP42251|PPBD_BACSU Alkaline phosphatase D (Gene Name=phoD)

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