Structure of PDB 2yep Chain B Binding Site BS01

Receptor Information
>2yep Chain B (length=213) Species: 1901 (Streptomyces clavuligerus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLLTFFATDARLDPAEQDRLFRRVMDRTFNAVSIDTDTSTSDTAVLFANG
LAGEVDAGEFEEALHTAALALVKDIASDGEGAAKLIEVQVTGARDDAQAK
RVGKTVVNSPLVKTAVHGCDPNWGRVAMAIGKCSDDTDIDQERVTIRFGE
VEVYPPKARGDQADDALRAAVAEHLRGDEVVIGIDLAIADGAFTVYGCDL
TEGYVRLNSEYTT
Ligand information
Ligand IDGLU
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKeyWHUUTDBJXJRKMK-VKHMYHEASA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@@H](C(=O)O)N
CACTVS 3.370N[C@@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameGLUTAMIC ACID
ChEMBLCHEMBL575060
DrugBankDB00142
ZINCZINC000001482113
PDB chain2yep Chain B Residue 1601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2yep Structural and Biochemical Analyses Reveal How Ornithine Acetyl Transferase Binds Acidic and Basic Amino Acid Substrates.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		X181 T393
Binding residue
(residue number reindexed from 1)		X1 T213
Annotation score5
Enzymatic activity
Enzyme Commision number 2.3.1.35: glutamate N-acetyltransferase.
Gene Ontology
Molecular Function
GO:0004358 glutamate N-acetyltransferase activity
Biological Process
GO:0006526 L-arginine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2yep, PDBe:2yep, PDBj:2yep
PDBsum2yep
PubMed21796301
UniProtP0DJQ5|GNAT2_STRCL Glutamate N-acetyltransferase 2 (Gene Name=oat2)

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