Structure of PDB 2xoz Chain B Binding Site BS01

Receptor Information

>2xoz Chain B (length=212) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

YVVCRQCPEYRRQAAQPPHCPDYVCPLQGSHALCTCCFQPMPDRRVEREQ
DPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVLN
NNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVLC
YCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHAM
KFNHICEQTRFK

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

2xoz Chain B Residue 991 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2xoz Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr).
Resolution	2.374 Å
Binding residue (original residue number in PDB)	C428 C476 H482
Binding residue (residue number reindexed from 1)	C4 C25 H31
Annotation score	4

Enzymatic activity

Enzyme Commision number

2.3.2.27: RING-type E3 ubiquitin transferase.

External links

PDB	RCSB:2xoz, PDBe:2xoz, PDBj:2xoz
PDBsum	2xoz
PubMed	20880844
UniProt	Q96EP1\|CHFR_HUMAN E3 ubiquitin-protein ligase CHFR (Gene Name=CHFR)

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