Structure of PDB 2xgq Chain B Binding Site BS01

Receptor Information
>2xgq Chain B (length=511) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRMSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSKE
DPVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKKG
EDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDL
VERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGGN
YDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGI
RDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDCG
KFEITSFWTLGGVLGKELIDVLDLPHENSIKHIRETWPDNAGQLKEFLDA
KVKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSSRPVVKSMMSN
KNLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTVSISLK
TKSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYYPLTK
LSMTITNFDII
Ligand information
Receptor-Ligand Complex Structure
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PDB2xgq Mechanism of Replication Blocking and Bypass of Y-Family Polymerase Eta by Bulky Acetylaminofluorene DNA Adducts.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
I437 I509
Binding residue
(residue number reindexed from 1)
I439 I511
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

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Molecular Function

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Biological Process
External links
PDB RCSB:2xgq, PDBe:2xgq, PDBj:2xgq
PDBsum2xgq
PubMed21076032
UniProtQ04049|POLH_YEAST DNA polymerase eta (Gene Name=RAD30)

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