Structure of PDB 2woo Chain B Binding Site BS01

Receptor Information
>2woo Chain B (length=303) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGTLENLLEQTSLKWIFVGGKGGVGKTTTSCSLAIQMSKVRSSVLLISTD
PAHNLSDAFGTKFGKDARKVPGFDNLSAMEIDPNLSIQEMTEQALSGMMQ
DLAFTIPGIDEALAFAEILKQIKSMEFDCVIFDTAPTGHTLRFLNFPTVL
EKALGKLGGLSSRFGPMINQMGSIMGQDLFGKMESMRANISEVNKQFKNP
DLTTFVCVCISEFLSLYETERMIQELTSYEIDTHNIVVNQLLLDPNTTCP
QCMARRKMQQKYLAQIEELYEDFHVVKVPQVPAEVRGTEALKSFSEMLVK
PYV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2woo Chain B Residue 1323 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2woo The Structural Basis of Tail-Anchored Membrane Protein Recognition by Get3.
Resolution3.006 Å
Binding residue
(original residue number in PDB)
C268 C271
Binding residue
(residue number reindexed from 1)
C249 C252
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G29 G31 K32 T33 T34 D56
Catalytic site (residue number reindexed from 1) G23 G25 K26 T27 T28 D50
Enzyme Commision number 3.6.-.-
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0032977 membrane insertase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0045048 protein insertion into ER membrane
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0043529 GET complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2woo, PDBe:2woo, PDBj:2woo
PDBsum2woo
PubMed19675567
UniProtQ9P7F8|GET3_SCHPO ATPase get3 (Gene Name=get3)

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