Structure of PDB 2w78 Chain B Binding Site BS01

Receptor Information
>2w78 Chain B (length=754) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQ
AITELLRGTGASVDFQGNAITISVQLGTITEDSGSYTPGTIATATRLVLT
PRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARG
FSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGS
LGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRA
VAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSG
WSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWV
GKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYL
TGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIG
KPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNP
TIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPD
EGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITY
AYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQD
QLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYW
LVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFST
RWDF
Ligand information
>2w78 Chain C (length=7) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SKGKKKS
Receptor-Ligand Complex Structure
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PDB2w78 Fpva Bound to Non-Cognate Pyoverdines: Molecular Basis of Siderophore Recognition by an Iron Transporter.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
R204 N228 G230 Y231 W362 Q446 Y448 W599 Y796
Binding residue
(residue number reindexed from 1)
R143 N167 G169 Y170 W301 Q385 Y387 W538 Y735
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015343 siderophore-iron transmembrane transporter activity
GO:0015344 siderophore uptake transmembrane transporter activity
GO:0038023 signaling receptor activity
Biological Process
GO:0002049 pyoverdine biosynthetic process
GO:0006826 iron ion transport
GO:0015891 siderophore transport
GO:0033214 siderophore-dependent iron import into cell
GO:0044718 siderophore transmembrane transport
Cellular Component
GO:0009279 cell outer membrane
GO:0016020 membrane
GO:0019867 outer membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2w78, PDBe:2w78, PDBj:2w78
PDBsum2w78
PubMed19504741
UniProtP48632|FPVA_PSEAE Ferripyoverdine receptor (Gene Name=fpvA)

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