Structure of PDB 2w35 Chain B Binding Site BS01

Receptor Information
>2w35 Chain B (length=223) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDYRQLHRWDLPPEEAIKVQNELRKKIKLTPYEGEPEYVAGVDLSFPGKE
EGLAVIVVLEYPSFKILEVVSERGEITFPYIPGLLAFREGPLFLKAWEKL
RTKPDVVVFDGQGLAHPRKLGIASHMGLFIEIPTIGVAKSRLYGTFKMPE
DKRCSWSYLYDGEEIIGCVIRTKEGSAPIFVSPGHLMDVESSKRLIKAFT
LPGRRIPEPTRLAHIYTQRLKKG
Ligand information
Receptor-Ligand Complex Structure
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PDB2w35 Structures of Endonuclease V with DNA Reveal Initiation of Deaminated Adenine Repair.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		K222 G223
Binding residue
(residue number reindexed from 1)		K222 G223
Enzymatic activity
Enzyme Commision number 3.1.21.7: deoxyribonuclease V.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003727 single-stranded RNA binding
GO:0004519 endonuclease activity
GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters
GO:0043737 deoxyribonuclease V activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2w35, PDBe:2w35, PDBj:2w35
PDBsum2w35
PubMed19136958
UniProtQ9X2H9|NFI_THEMA Endonuclease V (Gene Name=nfi)

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