Structure of PDB 2vwd Chain B Binding Site BS01

Receptor Information
>2vwd Chain B (length=410) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NICLQKTSNQILKPKLISYTLPTCITDPLLAMDEGYFAYSHLERIGSCSR
GVSKQRIIGVGEVLDRGDEVPSLFMTNVWTPPNPNTVYHCSAVYNNEFYY
VLCAVSTVGDPILNSTYWSGSLMMTRLAVKPKSNGGGYNQHQLALRSIEK
GRYDKVMPYGPSGIKQGDTLYFPAVGFLVRTEFKYNDSNCPITKCQYSKP
ENCRLSMGIRPNSHYILRSGLLKYNLSDGENPKVVFIEISDQRLSIGSPS
KIYDSLGQPVFYQASFSWDTMIKFGDVLTVNPLVVNWRNNTVISRPGQSQ
CPRFNTCPEICWEGVYNDAFLIDRINWISAGVFLDSNQTAENPVFTVFKD
NEILYRAQLASEDTNAQKTITNCFLLKNKIWCISLVEIYDTGDNVIRPKL
FAVKIPEQCT
Ligand information
Ligand IDGBL
InChIInChI=1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
InChIKeyYEJRWHAVMIAJKC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C1CC(=O)OC1
ACDLabs 10.04O=C1OCCC1
CACTVS 3.341O=C1CCCO1
FormulaC4 H6 O2
NameGAMMA-BUTYROLACTONE;
DIHYDROFURAN-2(3H)-ONE
ChEMBLCHEMBL95681
DrugBankDB04699
ZINCZINC000004658567
PDB chain2vwd Chain B Residue 1605 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2vwd Crystal Structure and Carbohydrate Analysis of Nipah Virus Attachment Glycoprotein: A Template for Antiviral and Vaccine Design.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		F458 W504 E505
Binding residue
(residue number reindexed from 1)		F266 W312 E313
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019058 viral life cycle
Cellular Component
GO:0019031 viral envelope

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2vwd, PDBe:2vwd, PDBj:2vwd
PDBsum2vwd
PubMed18815311
UniProtQ9IH62|GLYCP_NIPAV Glycoprotein G (Gene Name=G)

[Back to BioLiP]