Structure of PDB 2v3t Chain B Binding Site BS01

Receptor Information
>2v3t Chain B (length=254) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVLRVVTVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYV
APDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRY
MDYSVGVLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFE
RDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVA
INDPDCSFYTVTVADRGYGIALQHGSPYRDVFSQRILELQQSGDMDILKH
KWWP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2v3t Chain A Residue 1264 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2v3t Ionotropic Glutamate-Like Receptor {Delta}2 Binds D-Serine and Glycine.
Resolution2.75 Å
Binding residue
(original residue number in PDB)
D234 P258
Binding residue
(residue number reindexed from 1)
D230 P254
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:2v3t, PDBe:2v3t, PDBj:2v3t
PDBsum2v3t
PubMed17715062
UniProtQ63226|GRID2_RAT Glutamate receptor ionotropic, delta-2 (Gene Name=Grid2)

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