Structure of PDB 2rti Chain B Binding Site BS01

Receptor Information
>2rti Chain B (length=123) Species: 1895 (Streptomyces avidinii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDS
APATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTS
GTTEANAWKSTLVGHDTFTKVKP
Ligand information
Ligand IDGLL
InChIInChI=1S/C4H6N4O2/c9-3-5-1-2(7-3)8-4(10)6-1/h1-2H,(H2,5,7,9)(H2,6,8,10)/t1-,2+
InChIKeyVPVSTMAPERLKKM-XIXRPRMCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C12C(NC(=O)N1)NC(=O)N2
ACDLabs 10.04O=C1NC2NC(=O)NC2N1
CACTVS 3.341O=C1N[C@@H]2NC(=O)N[C@@H]2N1
CACTVS 3.341O=C1N[CH]2NC(=O)N[CH]2N1
FormulaC4 H6 N4 O2
NameGLYCOLURIL
ChEMBL
DrugBankDB03533
ZINC
PDB chain2rti Chain B Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2rti Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
Resolution1.4 Å
Binding residue
(original residue number in PDB)		L25 S27 Y43 S45 V47 T90 W108 D128
Binding residue
(residue number reindexed from 1)		L13 S15 Y31 S33 V35 T78 W96 D116
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:2rti, PDBe:2rti, PDBj:2rti
PDBsum2rti
PubMed9405158
UniProtP22629|SAV_STRAV Streptavidin

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