Structure of PDB 2rc9 Chain B Binding Site BS01

Receptor Information
>2rc9 Chain B (length=285) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSL
HSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNG
HWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRG
TELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPA
TPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYG
IGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYK
Ligand information
Ligand ID1AC
InChIInChI=1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)
InChIKeyPAJPWUMXBYXFCZ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341NC1(CC1)C(O)=O
OpenEye OEToolkits 1.5.0C1CC1(C(=O)O)N
ACDLabs 10.04O=C(O)C1(N)CC1
FormulaC4 H7 N O2
Name1-AMINOCYCLOPROPANECARBOXYLIC ACID
ChEMBLCHEMBL265325
DrugBankDB02085
ZINCZINC000000895536
PDB chain2rc9 Chain B Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2rc9 Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors.
Resolution1.96 Å
Binding residue
(original residue number in PDB)		Y97 S125 R130 S179 S180 D224
Binding residue
(residue number reindexed from 1)		Y94 S122 R127 S176 S177 D221
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:2rc9, PDBe:2rc9, PDBj:2rc9
PDBsum2rc9
PubMed18636091
UniProtQ9R1M7|NMD3A_RAT Glutamate receptor ionotropic, NMDA 3A (Gene Name=Grin3a)

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