Structure of PDB 2qxm Chain B Binding Site BS01
Receptor Information
>2qxm Chain B (length=242) Species:
9606
(Homo sapiens) [
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LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
Ligand information
>2qxm Chain D (length=10) Species:
10090
(Mus musculus) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2qxm
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I53 K57 L67 E75 D230 L231 E234
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2qxm
,
PDBe:2qxm
,
PDBj:2qxm
PDBsum
2qxm
PubMed
18344977
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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