Structure of PDB 2qt7 Chain B Binding Site BS01

Receptor Information
>2qt7 Chain B (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEEYGYIVTDQKPLSLAAGVKLLEILAEHVHMSSGSFINISVVGPALTFR
IRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQRE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2qt7 Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2qt7 Structure of the Mature Ectodomain of the Human Receptor-type Protein-tyrosine Phosphatase IA-2
Resolution1.3 Å
Binding residue
(original residue number in PDB)		E94 Q100
Binding residue
(residue number reindexed from 1)		E75 Q81
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Cellular Component
GO:0030141 secretory granule

View graph for
Cellular Component
External links
PDB RCSB:2qt7, PDBe:2qt7, PDBj:2qt7
PDBsum2qt7
PubMed18048354
UniProtQ16849|PTPRN_HUMAN Receptor-type tyrosine-protein phosphatase-like N (Gene Name=PTPRN)

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