Structure of PDB 2qse Chain B Binding Site BS01

Receptor Information
>2qse Chain B (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qse NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution1.85 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I53 K57 L67 V71 E75 D230 L231 E234
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2qse, PDBe:2qse, PDBj:2qse
PDBsum2qse
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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