Structure of PDB 2qgw Chain B Binding Site BS01

Receptor Information
>2qgw Chain B (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQL
LLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2qgw NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Resolution2.39 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 E76 D231 L232 E235
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2qgw, PDBe:2qgw, PDBj:2qgw
PDBsum2qgw
PubMed18344977
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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