Structure of PDB 2ps9 Chain B Binding Site BS01

Receptor Information

>2ps9 Chain B (length=265) Species: 562 (Escherichia coli)

AVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNAD
LVVWVGPEMEAFMQKPVSKLPGAKQVTIAQLEDVKPLLMKSIHGDFNMHL
WLSPEIARATAVAIHGKLVELMPQSRAKLDANLKDFEAQLASTETQVGNE
LAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHEIRTQ
LVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSE
FLSQLANQYASCLKG

Ligand information

• Ligand ID: CO
• InChI: InChI=1S/Co/q+2
• InChIKey: XLJKHNWPARRRJB-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Co+2]
  CACTVS 3.341: [Co++]
• Formula: Co
• Name: COBALT (II) ION
• DrugBank: DB14205
• PDB chain: 2ps9 Chain B Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2ps9 Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli.
• Resolution: 2.15 Å
• Binding residue (original residue number in PDB): E59 H60 H143 H207
• Binding residue (residue number reindexed from 1): E33 H34 H99 H163
• Annotation score: 3

Gene Ontology

Molecular Function

• GO:0008270 zinc ion binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006829 zinc ion transport
• GO:0007155 cell adhesion
• GO:0030001 metal ion transport
• GO:0071578 zinc ion import across plasma membrane

Cellular Component

• GO:0016020 membrane
• GO:0042597 periplasmic space
• GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

External links

• PDB: RCSB:2ps9, PDBe:2ps9, PDBj:2ps9
• PDBsum: 2ps9
• PubMed: 18027003
• UniProt: P39172|ZNUA_ECOLI High-affinity zinc uptake system protein ZnuA (Gene Name=znuA)