Structure of PDB 2prs Chain B Binding Site BS01

Receptor Information
>2prs Chain B (length=264) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNAD
LVVWVGPEMEAFMQKPVSKLPGAKQVTIAQLEDVKPLLMKSIDFNMHLWL
SPEIARATAVAIHGKLVELMPQSRAKLDANLKDFEAQLASTETQVGNELA
PLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHEIRTQLV
EQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFL
SQLANQYASCLKGD
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2prs Chain B Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2prs Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		E59 H60 H143 H207
Binding residue
(residue number reindexed from 1)		E33 H34 H97 H161
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006829 zinc ion transport
GO:0007155 cell adhesion
GO:0030001 metal ion transport
GO:0071578 zinc ion import across plasma membrane
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2prs, PDBe:2prs, PDBj:2prs
PDBsum2prs
PubMed18027003
UniProtP39172|ZNUA_ECOLI High-affinity zinc uptake system protein ZnuA (Gene Name=znuA)

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