Structure of PDB 2p1o Chain B Binding Site BS01

Receptor Information
>2p1o Chain B (length=571) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFPEEVLEHVFSFIQLDKDRNSVSLVCKSWYEIERWCRRKVFIGNCYAVS
PATVIRRFPKVRSVELKGKPHFADFNLVPDGWGGYVYPWIEAMSSSYTWL
EEIRLKRMVVTDDCLELIAKSFKNFKVLVLSSCEGFSTDGLAAIAATCRN
LKELDLRESDVDDVSGHWLSHFPDTYTSLVSLNISCLASEVSFSALERLV
TRCPNLKSLKLNRAVPLEKLATLLQRAPQLEELGTGGYTAEVRPDVYSGL
SVALSGCKELRCLSGFWDAVPAYLPAVYSVCSRLTTLNLSYATVQSYDLV
KLLCQCPKLQRLWVLDYIEDAGLEVLASTCKDLRELRVFPSEPFVMEPNV
ALTEQGLVSVSMGCPKLESVLYFCRQMTNAALITIARNRPNMTRFRLCII
EPKAPDYLTLEPLDIGFGAIVEHCKDLRRLSLSGLLTDKVFEYIGTYAKK
MEMLSVAFAGDSDLGMHHVLSGCDSLRKLEIRDCPFGDKALLANASKLET
MRSLWMSSCSVSFGACKLLGQKMPKLNVEVIDERGAPDSRPESCPVERVF
IYRTVAGPRFDMPGFVWNMDQ
Ligand information
>2p1o Chain C (length=13) Species: 3702 (Arabidopsis thaliana) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QVVGWPPVRNYRK
Receptor-Ligand Complex Structure
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PDB2p1o Mechanism of auxin perception by the TIR1 ubiquitin ligase
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D81 F82 S139 P350 F351 F380 C405 I407 R489
Binding residue
(residue number reindexed from 1)		D74 F75 S132 P343 F344 F373 C398 I400 R482
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000822 inositol hexakisphosphate binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0010011 auxin binding
GO:0038198 auxin receptor activity
Biological Process
GO:0006952 defense response
GO:0009733 response to auxin
GO:0009734 auxin-activated signaling pathway
GO:0009873 ethylene-activated signaling pathway
GO:0010152 pollen maturation
GO:0010311 lateral root formation
GO:0016036 cellular response to phosphate starvation
GO:0016567 protein ubiquitination
GO:0048443 stamen development
Cellular Component
GO:0005634 nucleus
GO:0019005 SCF ubiquitin ligase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2p1o, PDBe:2p1o, PDBj:2p1o
PDBsum2p1o
PubMed17410169
UniProtQ570C0|TIR1_ARATH Protein TRANSPORT INHIBITOR RESPONSE 1 (Gene Name=TIR1)

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