Structure of PDB 2p15 Chain B Binding Site BS01
Receptor Information
>2p15 Chain B (length=242) Species:
9606
(Homo sapiens) [
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LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL
LILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRLH
Ligand information
>2p15 Chain D (length=11) Species:
9606
(Homo sapiens) [
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KHKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
2p15
Structural plasticity in the oestrogen receptor ligand-binding domain.
Resolution
1.94 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 E542 M543
Binding residue
(residue number reindexed from 1)
I53 K57 L67 V71 E75 D230 E234 M235
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2p15
,
PDBe:2p15
,
PDBj:2p15
PDBsum
2p15
PubMed
17468738
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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