Structure of PDB 2oyi Chain B Binding Site BS01

Receptor Information
>2oyi Chain B (length=301) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVS
GKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQD
GSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGP
TELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGA
SQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRC
HAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPF
F
Ligand information
Receptor-Ligand Complex Structure
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PDB2oyi Probing the gamma2 Calcium-Binding Site: Studies with gammaD298,301A Fibrinogen Reveal Changes in the gamma294-301 Loop that Alter the Integrity of the "a" Polymerization Site.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		L360 M367 W385 E397 D398 R406 C407 H408 D432 M438
Binding residue
(residue number reindexed from 1)		L203 M210 W228 E240 D241 R249 C250 H251 D275 M281
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2oyi, PDBe:2oyi, PDBj:2oyi
PDBsum2oyi
PubMed17411074
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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