Structure of PDB 2ovr Chain B Binding Site BS01
Receptor Information
>2ovr Chain B (length=442) Species:
9606
(Homo sapiens) [
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TQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWR
ILAEDNLLWREKCKEEGIDEPLHIKRVIKPGFIHSPWKSAYIRQHRIDTN
WRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCL
RTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTV
RCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRV
VSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIR
VWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCL
QTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLE
SGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDM
Ligand information
>2ovr Chain C (length=8) [
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SLIPTPDK
Receptor-Ligand Complex Structure
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PDB
2ovr
Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
W2425 R2465 R2479 R2505 Y2519
Binding residue
(residue number reindexed from 1)
W161 R201 R215 R241 Y255
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2ovr
,
PDBe:2ovr
,
PDBj:2ovr
PDBsum
2ovr
PubMed
17434132
UniProt
Q969H0
|FBXW7_HUMAN F-box/WD repeat-containing protein 7 (Gene Name=FBXW7)
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