Structure of PDB 2ovq Chain B Binding Site BS01
Receptor Information
>2ovq Chain B (length=444) Species:
9606
(Homo sapiens) [
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TQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWR
ILAEDNLLWREKCKEEGIDEPLHIKRRKVIKPGFIHSPWKSAYIRQHRID
TNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGK
CLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTS
TVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGR
RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTS
IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQ
CLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT
LESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDM
Ligand information
>2ovq Chain C (length=12) [
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LPSGLLTPPQSG
Receptor-Ligand Complex Structure
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PDB
2ovq
Structure of a Fbw7-Skp1-Cyclin E Complex: Multisite-Phosphorylated Substrate Recognition by SCF Ubiquitin Ligases
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
W2425 S2462 T2463 R2465 R2479 R2505 Y2519 A2599 T2628 D2642 R2689
Binding residue
(residue number reindexed from 1)
W163 S200 T201 R203 R217 R243 Y257 A337 T366 D380 R427
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2ovq
,
PDBe:2ovq
,
PDBj:2ovq
PDBsum
2ovq
PubMed
17434132
UniProt
Q969H0
|FBXW7_HUMAN F-box/WD repeat-containing protein 7 (Gene Name=FBXW7)
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