Structure of PDB 2osv Chain B Binding Site BS01

Receptor Information
>2osv Chain B (length=263) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNAD
LVVWVGPEMEAFMQKPVSKLPGAKQVTIAQLEDVKPLLMKSIDFNMHLWL
SPEIARATAVAIHGKLVELMPQSRAKLDANLKDFEAQLASTETQVGNELA
PLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGAQRLHEIRTQLV
EQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFL
SQLANQYASCLKG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2osv Chain B Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2osv Crystal Structure of the Zinc-binding Transport Protein ZnuA from Escherichia coli Reveals an Unexpected Variation in Metal Coordination.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		E77 H78 H161 H225
Binding residue
(residue number reindexed from 1)		E33 H34 H97 H161
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006829 zinc ion transport
GO:0007155 cell adhesion
GO:0030001 metal ion transport
GO:0071578 zinc ion import across plasma membrane
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2osv, PDBe:2osv, PDBj:2osv
PDBsum2osv
PubMed17399739
UniProtP39172|ZNUA_ECOLI High-affinity zinc uptake system protein ZnuA (Gene Name=znuA)

[Back to BioLiP]