Structure of PDB 2oh2 Chain B Binding Site BS01

Receptor Information
>2oh2 Chain B (length=440) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQ
KAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDN
PELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPN
FDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRR
YFIKNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKN
KPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIITCTELY
QQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINK
AEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSV
VSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFP
Ligand information
Receptor-Ligand Complex Structure
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PDB2oh2 Ternary complex of the catalytic core of human DNA polymerase Kappa with DNA and dTT
Resolution3.05 Å
Binding residue
(original residue number in PDB)		S196 K321 G356 I357 G358 V360 T361 R454 T469 A471 S472 T473
Binding residue
(residue number reindexed from 1)		S176 K244 G279 I280 G281 V283 T284 R377 T392 A394 S395 T396
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2oh2, PDBe:2oh2, PDBj:2oh2
PDBsum2oh2
PubMed
UniProtQ9UBT6|POLK_HUMAN DNA polymerase kappa (Gene Name=POLK)

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