Structure of PDB 2o6h Chain B Binding Site BS01

Receptor Information

>2o6h Chain B (length=147) Species: 29459 (Brucella melitensis)

DAPHLLIVEARFYDDLADALLDGAKAALDEAGATYDVVTVPGALEIPATI
SFALDGADNGGTEYDGFVALGTVIRGETYHFDIVSNESCRALTDLSVEES
IAIGNGILTVENEEQAWVRARREDKDKGGFAARAALTMIGLRKKFGA

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 2o6h Chain B Residue 303

Receptor-Ligand Complex Structure

Structure summary

• PDB: 2o6h Structural and Kinetic Properties of Lumazine Synthase Isoenzymes in the Order Rhizobiales
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): A67 E73
• Binding residue (residue number reindexed from 1): A57 E63
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): H90
• Catalytic site (residue number reindexed from 1): H80
• Enzyme Commision number: 2.5.1.78: 6,7-dimethyl-8-ribityllumazine synthase.

Gene Ontology

Molecular Function

• GO:0000906 6,7-dimethyl-8-ribityllumazine synthase activity
• GO:0016740 transferase activity

Biological Process

• GO:0009231 riboflavin biosynthetic process

Cellular Component

• GO:0005829 cytosol
• GO:0009349 riboflavin synthase complex

External links

• PDB: RCSB:2o6h, PDBe:2o6h, PDBj:2o6h
• PDBsum: 2o6h
• PubMed: 17854827
• UniProt: Q8YGH2|RISB1_BRUME 6,7-dimethyl-8-ribityllumazine synthase 1 (Gene Name=ribH1)