Structure of PDB 2o1v Chain B Binding Site BS01

Receptor Information
>2o1v Chain B (length=575) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKI
KCDKEKNLLHVTDTGVGMTREELVKNLGTVGFYSAFLVADKVIVTSKHNN
DTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNL
VKKYSQFINFPIYVWSSKTVWDWELMNDIKPIWQRPSKEVEDDEYKAFYK
SFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAYIKLYVRRVFITDDFHD
MMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKK
IADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDITSL
DQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDE
YCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAIEKEFEPLLNWMKD
KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDIS
TNYYASQKKTFEINPRHPLIKDMLRRVKEDEDDKTVSDLAVVLFETATLR
SGYLLPDTKAYGDRIERMLRLSLNI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain2o1v Chain B Residue 756 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2o1v Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		D737 E740
Binding residue
(residue number reindexed from 1)		D563 E566
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:2o1v, PDBe:2o1v, PDBj:2o1v
PDBsum2o1v
PubMed17936703
UniProtP41148|ENPL_CANLF Endoplasmin (Gene Name=HSP90B1)

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