Structure of PDB 2nna Chain B Binding Site BS01

Receptor Information
>2nna Chain B (length=182) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSRDSPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYR
AVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPT
VTISPLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQIL
VMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2nna A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease
Resolution2.1 Å
Binding residue
(original residue number in PDB)		F11 G13 C15 L26 Y30 Y37 Y47 Y60 W61 R70 E74 V78 H81 N82 L85
Binding residue
(residue number reindexed from 1)		F13 G15 C17 L28 Y32 Y39 Y49 Y62 W63 R72 E76 V80 H83 N84 L87
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2nna, PDBe:2nna, PDBj:2nna
PDBsum2nna
PubMed17629515
UniProtP01920|DQB1_HUMAN HLA class II histocompatibility antigen, DQ beta 1 chain (Gene Name=HLA-DQB1)

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