Structure of PDB 2nad Chain B Binding Site BS01

Receptor Information
>2nad Chain B (length=383) Species: 33067 (Pseudomonas sp. 101) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKVLCVLYDDPVDGYPKTYARDDLPKIDHYPGGQTLPTPKAIDFTPGQLL
GSVSGELGLRKYLESNGHTLVVTSDKDGPDSVFERELVDADVVISQPFWP
AYLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRNVTVAEVTYCNSISV
AEHVVMMILSLVRNYLPSHEWARKGGWNIADCVSHAYDLEAMHVGTVAAG
RIGLAVLRRLAPFDVHLHYTDRHRLPESVEKELNLTWHATREDMYPVCDV
VTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESG
RLAGYAGDVWFPQPAPKDHPWRTMPYNGMTPHISGTTLTAQARYAAGTRE
ILECFFEGRPIRDEYLIVQGGALAGTGAHSYSK
Ligand information
Ligand IDAZI
InChIInChI=1S/N3/c1-3-2/q-1
InChIKeyIVRMZWNICZWHMI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[N-]=[N+]=[N-]
FormulaN3
NameAZIDE ION
ChEMBLCHEMBL79455
DrugBank
ZINC
PDB chain2nad Chain B Residue 395 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2nad High resolution structures of holo and apo formate dehydrogenase.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		P97 F98 I122 N146 R284 H332
Binding residue
(residue number reindexed from 1)		P97 F98 I122 N146 R284 H332
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) N146 R284 D308 Q313 H332
Catalytic site (residue number reindexed from 1) N146 R284 D308 Q313 H332
Enzyme Commision number 1.17.1.9: formate dehydrogenase.
Gene Ontology
Molecular Function
GO:0008863 formate dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding
Biological Process
GO:0042183 formate catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2nad, PDBe:2nad, PDBj:2nad
PDBsum2nad
PubMed8114093
UniProtP33160|FDH_PSESR Formate dehydrogenase

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