Structure of PDB 2m2n Chain B Binding Site BS01

Receptor Information
>2m2n Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGHFYTPKT
Ligand information
>2m2n Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB2m2n Structural integrity of the B24 site in human insulin is important for hormone functionality.
ResolutionN/A
Binding residue
(original residue number in PDB)		F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F25 Y26
Binding residue
(residue number reindexed from 1)		F1 N3 Q4 H5 L6 C7 L11 L15 V18 C19 R22 G23 F25 Y26
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:2m2n, PDBe:2m2n, PDBj:2m2n
PDBsum2m2n
PubMed23447530
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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