Structure of PDB 2m1e Chain B Binding Site BS01

Receptor Information
>2m1e Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTKPT
Ligand information
>2m1e Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB2m1e Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.
ResolutionN/A
Binding residue
(original residue number in PDB)
F1 N3 H5 L6 C7 L11 A14 L15 V18 C19 R22 G23 F24 F25 Y26 P29
Binding residue
(residue number reindexed from 1)
F1 N3 H5 L6 C7 L11 A14 L15 V18 C19 R22 G23 F24 F25 Y26 P29
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:2m1e, PDBe:2m1e, PDBj:2m1e
PDBsum2m1e
PubMed23404086
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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