Structure of PDB 2l51 Chain B Binding Site BS01

Receptor Information
>2l51 Chain B (length=102) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDCYTELEKAVIVLVENFYKYVSKYSLVKNKISKSSFREMLQKELNHMLS
DTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGITGPIAKLIHEQEQQS
SS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2l51 Chain B Residue 209 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2l51 Structural characterization of human S100A16, a low-affinity calcium binder.
ResolutionN/A
Binding residue
(original residue number in PDB)		Y125 V126 S127 Y129 S130 L131 K135
Binding residue
(residue number reindexed from 1)		Y21 V22 S23 Y25 S26 L27 K31
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0051592 response to calcium ion
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2l51, PDBe:2l51, PDBj:2l51
PDBsum2l51
PubMed21046186
UniProtQ96FQ6|S10AG_HUMAN Protein S100-A16 (Gene Name=S100A16)

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