Structure of PDB 2k2f Chain B Binding Site BS01

Receptor Information
>2k2f Chain B (length=93) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSELETAMETLINVFHAHSGKEGDKYKLSKKELKDLLQTELSSFLDVQKD
ADAVDKIMKELDENGDGEVDFQEFVVLVAALTVACNNFFWENS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2k2f S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor.
ResolutionN/A
Binding residue
(original residue number in PDB)		K56 I57 L77 L81
Binding residue
(residue number reindexed from 1)		K56 I57 L77 L81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044548 S100 protein binding
GO:0046872 metal ion binding
GO:0048306 calcium-dependent protein binding
GO:0051117 ATPase binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0008016 regulation of heart contraction
GO:1903672 positive regulation of sprouting angiogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016529 sarcoplasmic reticulum
GO:0030018 Z disc
GO:0031430 M band
GO:0031672 A band
GO:0031674 I band

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2k2f, PDBe:2k2f, PDBj:2k2f
PDBsum2k2f
PubMed18650434
UniProtP35467|S10A1_RAT Protein S100-A1 (Gene Name=S100a1)

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