Structure of PDB 2jfa Chain B Binding Site BS01

Receptor Information
>2jfa Chain B (length=223) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLA
QLLLILSHIRHMSNKGMEHLYSM
Ligand information
>2jfa Chain Q (length=15) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DAFQLRQLILRGLQD
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2jfa Structural Insights Into Corepressor Recognition by Antagonist-Bound Estrogen Receptors.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		L354 I358 K362 V376 E380 W383
Binding residue
(residue number reindexed from 1)		L49 I53 K57 V71 E75 W78
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2jfa, PDBe:2jfa, PDBj:2jfa
PDBsum2jfa
PubMed17283072
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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