Structure of PDB 2je4 Chain B Binding Site BS01

Receptor Information
>2je4 Chain B (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PQITLWKRPLVTIRIGGQLKEALLDTGADDTVIEELNLPGKWKPKLIGGI
GGFIKVRQYDQIPVEITGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Ligand information
Receptor-Ligand Complex Structure
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PDB2je4 Modular Total Chemical Synthesis of a Human Immunodeficiency Virus Type 1 Protease.
Resolution1.07 Å
Binding residue
(original residue number in PDB)		D25 G27 A28 D29 G48 V82 I84
Binding residue
(residue number reindexed from 1)		D25 G27 A28 D29 G48 V82 I84
Enzymatic activity
Catalytic site (original residue number in PDB) D25 T26 G27
Catalytic site (residue number reindexed from 1) D25 T26 G27
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2je4, PDBe:2je4, PDBj:2je4
PDBsum2je4
PubMed17705484
UniProtP03369|POL_HV1A2 Gag-Pol polyprotein (Gene Name=gag-pol)

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